Funds earmarked for “integrated biological and computational low-dose radiation research” will go to 14 university research projects in a new approach to federally funded low-dose radiation research that leverages artificial intelligence and machine learning to find cellular markers of radiation health effects. The Department of Energy announced on August 21 that these 14 projects on cellular and molecular responses to low-dose radiation would collectively get $19.5 million in funding over three years.

The Manhattan Project may have begun more than 80 years ago, but it’s still in the news—and not just because of Oppenheimer’s recent haul at the Academy Awards. On March 7, the Senate passed S. 3853, the Radiation Exposure Compensation Reauthorization Act, by a vote of 69 to 30, sending the bill to the House. It’s Sen. Josh Hawley's (R., Mo.) second attempt to reauthorize the Radiation Exposure Compensation Act (RECA)—which was first enacted in 1990 to address the legacy of U.S. nuclear weapons production—before it expires in June. The bill would extend the deadline to claim compensation by five years and expand it from the dozen states now covered to include individuals exposed to radiation in certain regions of Missouri, Alaska, Kentucky, and Tennessee.

New appropriations bills currently under review in the U.S. Congress include a significant funding boost for nuclear energy.

This week, ranking members of both the U.S. House and Senate released six fiscal year 2024 appropriations, including the Energy and Water Development and Related Agencies bill that has nuclear energy funding for FY 2024.

A group of researchers analyzed recent updates to the International Nuclear Workers Study (INWORKS) and published their findings—“Cancer mortality after low dose exposure to ionising radiation in workers in France, the United Kingdom, and the United States (INWORKS): cohort study”—in the journal BMJ on August 16. The multinational research team, led by David B. Richardson of the University of California–Irvine, reports “evidence of an increase in the excess relative rate of solid cancer mortality with increasing cumulative exposure to ionizing radiation at the low dose rates typically encountered by French, U.K., and U.S. nuclear workers [and] evidence in support of a linear association between protracted low dose external exposure to ionizing radiation and solid cancer mortality.”

NASA’s Artemis I mission, successfully launched at 1:47 a.m. EST on November 16 from the Kennedy Space Center in Florida, will travel 40,000 miles beyond the moon—farther from Earth than any human-crewed space mission has flown before. The historic trip was launched by the world’s largest rocket, the Space Launch System (SLS), nearly 50 years after NASA last sent humans to the moon. And while no humans are on board the Orion spacecraft, two fabricated crew members—“Luna Twins” Helga and Zohar—were assembled with thousands of sensors to obtain the best estimates yet of cosmic radiation exposure to human tissues during space travel.

The June 2017 special report on the ANS Nuclear Grand Challenges (available online at ans.org/challenges/) identified low-dose radiation as a crucial focus area for ANS. Specifically, the challenge is to “Establish the scientific basis for modern low-dose radiation regulation.” This is particularly difficult given the long review cycles associated with International Commission on Radiological Protection (ICRP) and National Council on Radiation Protection and Measurements (NCRP) recommendations. Additionally, while the Environmental Protection Agency is tasked with issuing guidance on radiation exposure standards in the United States, responsibility for implementing and enforcing radiation protection regulations is distributed throughout the federal government. Finally, while it is accepted that tissue reactions (previously called deterministic or nonstochastic effects) exhibit a dose threshold, there is still substantial scientific debate over the shape of the dose response at low doses for stochastic effects, such as cancer. Despite these hurdles, substantial progress has been made over the past five years on the low-dose radiation grand challenge.

The National Academies of Science, Engineering, and Mathematics released a report in June recommending that the United States invest a total of $1.5 billion in low-dose radiation research over the next 15 years. Congress is working through the Fiscal Year 2023 appropriations process at this writing, and many in the nuclear community are hopeful that research programs that have been starved of funding and leadership will be reinvigorated and bring long-overdue clarity to questions of low-dose radiation science, policy, and regulation.

The United States could invest a total of $1.5 billion in low-dose radiation research over the next 15 years if Congress, the Department of Energy, the National Institutes of Health, and other stakeholders carry out the recommendations set forth in a National Academies of Science, Engineering, and Mathematics report released in June.

Join ANS Executive Director/CEO Craig Piercy on July 15 at 12 p.m. (EDT) for a free public webinar—“High Expectations for the Future of Low-Dose Radiation Research"—on the impact of the National Academies report as the U.S. embarks on a new era of low-dose radiation research.

A new report from the National Academies of Sciences, Engineering, and Medicine (NASEM) estimates that $100 million annually will be required for the next 15 years to develop a coordinated research program led by the Department of Energy and the National Institutes of Health to study how low doses of radiation affect disease risk. The recommended research would investigate causal links to specific health conditions and better define the impacts of radiation doses, dose rates, types of radiation, and exposure duration.

Early in my year as ANS vice president/president-elect, I was determined to try to find a project that the entire ANS community could rally behind and could be completed during my year as ANS president. I was looking for something that would provide community-identified focus areas for future activities and that would mobilize, energize, and inspire ANS members during that year and in the years ahead.

The biggest impact of radiation in our lives may come not from radiation itself, but from regulations and guidelines intended to control exposures to man-made sources that represent a small fraction of the natural radiation around us.

Decades of research have been unable to discern clear health impacts from low levels of ionizing radiation, leading to calls for a new research program—one with a strategic research agenda focused on how the scientific understanding of the health effects of low doses (below 100 millisievert) and low dose rates (less than 5 mSv per hour) can best be augmented, applied, and communicated.

What is one thing that bridges, oil wells, and cancer treatment therapies have in common? Reliance on radioisotopes. Radioisotopes have played an important role in our society for decades, yet their benefits often go unrecognized. As Congress makes progress on new bipartisan infrastructure legislation, radioisotopes are essential to bringing new infrastructure projects to life.

The United States is embarking on a new coordinated federal low-dose radiation research program. With guidance from the National Academies of Sciences, Engineering, and Medicine, the Department of Energy’s Office of Science will build a program that integrates the research of past decades, but without treading the same well-worn path. Instead, the new program will focus on how the scientific understanding of low-dose radiation can best be augmented, applied, and communicated.

Join ANS on Thursday, January 21, at noon (ET) for a Q&A with an expert panel as they discuss how to communicate about the risk of low-dose radiation. “Talking About Low-dose Radiation Risk” is a free members-only event that serves as a follow-up to the “Risky Business” President’s Session that took place during the ANS Virtual Winter Meeting last November. The session will take a deeper dive into the many questions generated from the thought-provoking discussion.

Register now to attend the webinar.

ANS President Mary Lou Dunzik-Gougar took to the video screen on November 18 during the 2020 ANS Virtual Winter Meeting for the President’s Special Session on radiation risk, echoing a comment by Exelon Nuclear’s Bryan Hanson, the Winter Meeting’s general cochair, who earlier in the week characterized radiation as one of the most misunderstood aspects of nuclear.

“I think that’s very true,” Dunzik-Gougar said. “So much misconception and misunderstanding. I have always had a passion for communicating about such things as radiation, helping people understand the nature of radiation and the relative risks of nuclear, but mostly about its benefits. But I think we in the industry can better prepare ourselves with knowledge about radiation and its impacts and also educate ourselves on how to talk about the risks of radiation with people not in our own echo chambers to help change the perception among a broader scope of people.”

The panel of experts assembled to help impart some of that knowledge to session attendees included Amir A. Bahadori, assistant professor at Kansas State University; Donald A. Cool, a technical executive at the Electric Power Research Institute and a former senior executive at the Nuclear Regulatory Commission; Paul Locke, associate professor at the Johns Hopkins Bloomberg School of Public Health; and Shaheen Dewji, assistant professor at Texas A&M University.

Craig Piercy

Originally published in the September 2020 issue of Nuclear News.

This issue of Nuclear News is dedicated to highlighting advancements in health physics and radiation protection as well as the contributions of the men and women who serve in these fields. It comes at a time when COVID-19 is providing the entire world with an immersive primer on the science of epidemiology and the importance of risk-informed, performance-based behavior to contain an invisible—yet deadly—antagonist.

The National Academies of Sciences, Engineering, and Medicine (NAS) has begun a new webinar series, with the first entry titled “What’s new in low-dose radiation.” The July 22 event kicked off the Gilbert W. Beebe Webinar Series—an extension of the Beebe Symposium, which was established in 2002 to honor the scientific achievements of the late Gilbert Beebe, NAS staff member and designer/implementer of epidemiologic studies of populations exposed to the atomic bombings of Hiroshima and Nagasaki as well as the Chernobyl accident.